Determination of levamisole by HPLC in plasma samples in the presence of heparin and pentobarbital

Repositorio Dspace/Manakin

Determination of levamisole by HPLC in plasma samples in the presence of heparin and pentobarbital

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Título: Determination of levamisole by HPLC in plasma samples in the presence of heparin and pentobarbital
Autor: García, Juan J.;Diez, M. José;Sierra, Matilde;Terán, M. Teresa
Facultad/Centro: Facultad de Veterinaria
Area de conocimiento: Farmacologia
Resumen: A method which allows for the isolation of levamisole in plasma samples of rabbit which contained pentobarbital and heparin as well, used as an anaesthetic and an anticoagulant respectively, is described in this paper. The subsequent quantification was carried out using a ion-pair high-performance liquid chromatographic method in a reversed and isocratic phase at room temperature, using a UV detection at 225nm. In our conditions the retention time for the levamisole was about 2.15 minutes and the average percentage of recuperation was that of 73.62%.
Descripción física: P. 743-749
Revisión por pares: SI
Editor: Taylor and Francis
Datos: Journal of liquid Chromatography, 1990, n. 13
URI: http://hdl.handle.net/10612/4409
Fecha: 1990-06-20
Tipo: info:eu-repo/semantics/article
Materia: Ecología. Medio ambiente
Farmacología
Zoología
Palabras clave: Pentobarbital
Heparina
Levamisol
HPLC
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